SCHEMBL994964

SCHEMBL994964

O=C(Cl)c1ccc(C=Cc2ccc(C(=O)Cl)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.48
ALDH1A1 P00352 3/20 0.46
PRMT5 O14744 1/20 0.46
PRMT1 Q99873 1/20 0.46
HPGD P15428 1/20 0.46
CYP2C19 P33261 1/20 0.46
HSD17B10 Q99714 1/20 0.46
KDM1A O60341 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
F3 P13726 2/20 0.45
MAPT P10636 1/20 0.43
TNFRSF1A P19438 1/20 0.43
CYP1A2 P05177 1/20 0.43
MAOB P27338 3/20 0.42
CXCL12 P48061 1/20 0.42
MAOA P21397 1/20 0.41
SNCA P37840 1/20 0.41
FBP1 P09467 1/20 0.41
PTPN1 P18031 1/20 0.40
CYP1B1 Q16678 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL994963 1.00 HDAC1 (0.48) HDAC1ALDH1A1PRMT5PRMT1HPGD
SCHEMBL9679271 1.00 HDAC1 (0.48) HDAC1ALDH1A1PRMT5PRMT1HPGD
Hydrochloric Acid SCHEMBL7751049 0.97 HDAC1 (0.47) HDAC1ALDH1A1PRMT5PRMT1HPGD
SCHEMBL10704031 0.91 ALDH1A1 (0.56) HDAC1ALDH1A1PRMT5PRMT1HPGD
SCHEMBL10460408 0.91 HDAC1 (0.62) HDAC1ALDH1A1HDAC6F3MAPT
SCHEMBL10460407 0.91 HDAC1 (0.62) HDAC1ALDH1A1HDAC6F3MAPT
SCHEMBL10704028 0.91 ALDH1A1 (0.56) HDAC1ALDH1A1PRMT5PRMT1HPGD
SCHEMBL14984235 0.89 MAPT (0.60) HDAC1ALDH1A1HPGDHDAC6MAPT
SCHEMBL5692757 0.89 HDAC1 (0.46) HDAC1ALDH1A1PRMT5PRMT1HPGD
SCHEMBL25202703 0.87 HDAC1 (0.65) HDAC1ALDH1A1HPGDCYP2C19KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0583888-B2 Water-dispersible UV light-absorbing copolymer UNILEVER PLC (GB) 2001-01-17 EP claimed
US-5698183-A MODIFIED POLYESTER OR POLYAMIDE; SUNSCREEN AGENT LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-12-16 US claimed
EP-0583888-A1 Water-dispersible UV light-absorbing copolymer UNILEVER PLC (GB) 1994-02-23 EP claimed
WO-1993022366-A1 WATER-DISPERSIBLE COPOLYMER CONTAINING UVA AND UVB LIGHT-ABSORBING MONOMERS UNILEVER PLC (GB) 1993-11-11 WO claimed
US-5250652-A High loading water-dispersible UVA and/or UVB light-absorbing copolymer LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1993-10-05 US claimed
US-5243021-A Polylactam, polyester, polyether copolymers containing stilbene groups LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1993-09-07 US claimed
US-4533505-A REACTION OF ETHYLENE IWITH ACID HALIDES IN THE PRESENCE OF A BASE AND A PALLADIUM CATALYST CIBA-GEIGY CORPORATION (US) 1985-08-06 US claimed
EP-0062005-B1 PROCESS FOR THE MANUFACTURE OF STYRENE AND/OR STILBENE DERIVATIVES CIBA-GEIGY AG (CH) 1985-06-26 EP claimed
US-12570894-B2 Photochromic compound and curable composition containing the photochromic compound TOKUYAMA CORPORATION (JP) 2026-03-10 US disclosed
US-12321132-B2 Resin composition, toner for developing electrostatic charge image, image forming method, photosensitive adhesive, and optical switching material Konica Minolta, Inc. (JP) 2025-06-03 US disclosed
CN-119264009-A Photoisomerization chiral hydrogel material and preparation method and application thereof 河南大学 2025-01-07 CN disclosed
US-20240101751-A1 HOLLOW MICROBALLOON TOKUYAMA CORPORATION (JP) 2024-03-28 US disclosed
US-20230390890-A1 POLYMERIZABLE FUNCTIONAL GROUP-CONTAINING MICROBALLOON TOKUYAMA CORPORATION (JP) 2023-12-07 US disclosed
EP-4286439-A1 HOLLOW MICROBALLOON Tokuyama Corporation (JP) 2023-12-06 EP disclosed
US-5136013-A Polyesters BAYER AKTIENGESELLSCHAFT (DE) 1992-08-04 US disclosed
US-4782187-A Process for the preparation of 4,4'-stilbenedialdehydes CIBA-GEIGY CORPORATION (US) 1988-11-01 US disclosed
US-4684744-A Stilbene derivatives Ciga-Geiby Corporation (US) 1987-08-04 US disclosed
US-4440694-A FROM STILBENE DIACYL HALIDES, PALLADIUM CATALYST CIBA-GEIGY CORPORATION (US) 1984-04-03 US disclosed
US-4335055-A Process for the preparation of alkenylbenzene derivatives or alkenylnaphthalene derivatives CIBA-GEIGY CORPORATION (US) 1982-06-15 US disclosed
US-3935195-A FLUORESCENT DYE STERLING DRUG INC. (US) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570894-B2 Photochromic compound and curable composition containing the photochromic compound SMC4, HBG2, SPTBN1 HDAC1 776/4885ALDH1A1 2699/4885PRMT5 501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.