Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10181063 | 0.85 | HPGD (0.36) | HTR2ACYP3A4KMT2AKDM4EMEN1 | |
| Water SCHEMBL9950293 | 0.85 | HPGD (0.36) | HTR2ACYP3A4KMT2AKDM4EMEN1 | |
| Water SCHEMBL10179923 | 0.85 | HPGD (0.38) | HTR2ACYP3A4KMT2AKDM4EMEN1 | |
| Water SCHEMBL9950902 | 0.85 | HPGD (0.36) | HTR2ACYP3A4KMT2AKDM4EMEN1 | |
| Water SCHEMBL9949277 | 0.85 | HPGD (0.36) | HTR2ACYP3A4KMT2AKDM4EMEN1 | |
| Water SCHEMBL10179762 | 0.79 | PKM (0.43) | KDM4EALDH1A1CYP1A2HPGDPKM | |
| Water SCHEMBL9949680 | 0.79 | PKM (0.43) | KDM4EALDH1A1CYP1A2HPGDPKM | |
| SCHEMBL9615012 | 0.72 | HPGD (0.34) | KMT2AKDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL891328 | 0.69 | HPGD (0.59) | CYP3A4KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL29706732 | 0.66 | HPGD (0.51) | CYP3A4KDM4EALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2474535-B1 | SYNTHETIC METHOD OF MONTELUKAST SODIUM INTERMEDIATE | SHANDONG NEW TIME PHARMACEUTICAL CO LTD (CN) | 2014-07-02 | — | — | EP | disclosed |
| US-8569508-B2 | Synthetic method for montelukast sodium intermediate | SHANDONG NEW TIME PHARMACEUTICAL CO., LTD. (CN) | 2013-10-29 | — | — | US | disclosed |
| EP-2474535-A1 | SYNTHETIC METHOD OF MONTELUKAST SODIUM INTERMEDIATE | Shandong New Time Pharmaceutical Co., Ltd. (CN) | 2012-07-11 | — | — | EP | disclosed |
| US-20120165535-A1 | SYNTHETIC METHOD FOR MONTELUKAST SODIUM INTERMEDIATE | SHANDONG NEW TIME PHARMACEUTICAL CO. LTD. (CN) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165535-A1 | SYNTHETIC METHOD FOR MONTELUKAST SODIUM INTERMEDIATE | LTC4S, CMA1, PTGIS | HTR2A 1762/4885CYP3A4 268/4885KMT2A 1965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.