Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2023098 | 1.00 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6580033 | 1.00 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL7719205 | 1.00 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14563550 | 0.95 | — | — | |
| Bicarbonate SCHEMBL5189020 | 0.95 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9012479 | 0.94 | — | — | |
| Bicarbonate SCHEMBL472826 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL28897502 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL231029 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2953263 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170077403-A1 | METHOD FOR FABRICATING LARGE METAL NANOFIBER ELECTRODE ARRAY USING ALIGNED METAL NANOFIBER | POSTECH ACADEMY- INDUSTRY FOUNDATION (KR) | 2017-03-16 | — | — | US | claimed |
| US-20170077403-A1 | METHOD FOR FABRICATING LARGE METAL NANOFIBER ELECTRODE ARRAY USING ALIGNED METAL NANOFIBER | POSTECH ACADEMY- INDUSTRY FOUNDATION (KR) | 2017-03-16 | — | — | US | disclosed |
| US-20160374209-A1 | METHOD OF FABRICATING METAL NANOWIRE PATTERN | POSTECH ACADEMY - INDUSTRY FOUNDATION (KP) | 2016-12-22 | — | — | US | disclosed |
| US-9353025-B2 | Process for selective removal of acetylenes from gaseous streams | TPC GROUP LLC (US) | 2016-05-31 | — | — | US | disclosed |
| US-20150315107-A1 | Process for Selective Removal of Acetylenes from Gaseous Streams | TPC GROUP LLC | 2015-11-05 | — | — | US | disclosed |
| US-9115038-B2 | Process for selective removal of acetylenes from gaseous streams | TPC GROUP LLC (US) | 2015-08-25 | — | — | US | disclosed |
| US-20120164048-A1 | PROCESS FOR SELECTIVE REMOVAL OF ACETYLENES FROM GASEOUS STREAMS | TPC GROUP LLC | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150315107-A1 | Process for Selective Removal of Acetylenes from Gaseous Streams | FAR1, ACSL4, TECR | CA4 1909/4885CA1 3843/4885FAHD1 631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.