Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL6580033 | 1.00 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9950130 | 1.00 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL7719205 | 1.00 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14563550 | 0.95 | — | — | |
| Bicarbonate SCHEMBL5189020 | 0.95 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9012479 | 0.94 | — | — | |
| Bicarbonate SCHEMBL472826 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL28897502 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL231029 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2953263 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112262128-A | Method for forming aryl carbon-nitrogen bond by illumination and photoreactor for carrying out the reaction | 科罗拉多州立大学研究基金会 | 2021-01-22 | — | — | CN | claimed |
| WO-2019152524-A1 | METHODS FOR STABILIZING BACTERIAL PROBIOTIC COMPOSITIONS | BiOWiSH Technologies, Inc. (US) | 2019-08-08 | — | — | WO | claimed |
| US-20190231882-A1 | METHODS FOR STABILIZING BACTERIAL PROBIOTIC COMPOSITIONS | BIOWISH TECHNOLOGIES, INC., ASSIGNOR | 2019-08-01 | — | — | US | claimed |
| US-20170271637-A1 | METHOD OF MANUFACTURING POROUS POLYMER MEMBRANE USING WATER PRESSURE AND BATTERY SEPARATOR COMPRISING POROUS POLYMER MEMBRANE MANUFACTURED BY THE METHOD | SANGMYUNG UNIVERSITY SEOUL INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) | 2017-09-21 | — | — | US | claimed |
| US-9717767-B2 | Compositions and methods for improving human health and nutrition | BiOWiSH Technologies, Inc. (US) | 2017-08-01 | — | — | US | claimed |
| WO-2015175536-A1 | COMPOSITIONS AND METHODS FOR IMPROVING HUMAN HEALTH AND NUTRITION | BiOWiSH Technologies, Inc. (US) | 2015-11-19 | — | — | WO | claimed |
| US-20150320809-A1 | COMPOSITIONS AND METHODS FOR IMPROVING HUMAN HEALTH AND NUTRITION | BIOWISH TECHNOLOGIES, INC., ASSIGNOR | 2015-11-12 | — | — | US | claimed |
| WO-2007140525-A1 | A METHOD OF TREATMENT AND PROPHYLAXIS OF EVENTS, CONDITIONS AND DISEASES OF THE SYSTEMIC VASCULATURE AN IMMUNE FUNCTION TO DECREASE CARDIOVASCULAR RISK AND PATHOGENIC INFECTION | HOENIG MICHEL (AU) | 2007-12-13 | — | — | WO | claimed |
| US-20260125603-A1 | ISOMERIZATION OF BIOFEEDS OVER BASE METAL CATALYSTS | EXXONMOBIL TECHNOLOGY AND ENGINEERING CO (US) | 2026-05-07 | — | — | US | disclosed |
| US-12503654-B2 | Reduced H2 consumption during deoxygenation | ExxonMobil Technology and Engineering Company (US) | 2025-12-23 | — | — | US | disclosed |
| US-12503655-B2 | Isomerization of biofeeds over base metal catalysts | ExxonMobil Technology and Engineering Company (US) | 2025-12-23 | — | — | US | disclosed |
| EP-4642870-A1 | BASE METAL ISOMERIZATION CATALYSTS | ExxonMobil Technology and Engineering Company (US) | 2025-11-05 | — | — | EP | disclosed |
| EP-4642877-A1 | ISOMERIZATION OF BIOFEEDS OVER BASE METAL CATALYSTS | ExxonMobil Technology and Engineering Company (US) | 2025-11-05 | — | — | EP | disclosed |
| US-20250257315-A1 | CARBO-IONIC CULTURES AND EXTRACTS AND APPLICATIONS THEREOF | Bio Capital Holdings, LLC | 2025-08-14 | — | — | US | disclosed |
| WO-2007140525-A1 | A METHOD OF TREATMENT AND PROPHYLAXIS OF EVENTS, CONDITIONS AND DISEASES OF THE SYSTEMIC VASCULATURE AN IMMUNE FUNCTION TO DECREASE CARDIOVASCULAR RISK AND PATHOGENIC INFECTION | HOENIG MICHEL (AU) | 2007-12-13 | — | — | WO | disclosed |
| US-6693154-B2 | AN ORGANOMETALLIC COMPLEX CONTAINS A TRANSITION OR LANTHANIDE METAL AND 1,3-BIS(ARYLIMINO)ISOINDOLINE OR 1,3-BIS(HETEROARYLIMINO) ISOINDOLINE; ETHYLENE COPOLYMER WITH HIGH MOLECULAR WEIGHT, BROAD MOLECULAR WEIGHT DISTRIBUTION | EQUISTAR CHEMICALS, LP | 2004-02-17 | — | — | US | disclosed |
| US-20030065113-A1 | Transition metal catalysts for olefin polymerization | EQUISTAR CHEMICALS, LP | 2003-04-03 | — | — | US | disclosed |
| US-6383975-B1 | CATALYTIC HYDROTREATMENT OF MIDDLE AND HEAVY OILS, IMPREGNATION OF GROUP IVB METAL ON ALUMINA, DRYING AND ROASTING IMPREGNATION OF THE ALUMINA WITH A TI COMPOUND, SOLUBLE IN AN ORGANIC SOLVENT, | INSTITUTO MEXICANO DEL PETROLEO (MX) | 2002-05-07 | — | — | US | disclosed |
| US-5167876-A | Protective clothing; military aircraft interiors | ALLIED-SIGNAL INC. (US) | 1992-12-01 | — | — | US | disclosed |
| WO-1992010363-A1 | FLAME RESISTANT BALLISTIC COMPOSITE | ALLIED-SIGNAL INC. (US) | 1992-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125603-A1 | ISOMERIZATION OF BIOFEEDS OVER BASE METAL CATALYSTS | CYP4F8, SLC6A12, DBF4 | CA4 78/4885CA1 109/4885FAHD1 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.