SCHEMBL995046

SCHEMBL995046

CC1(C)CC(/C(=C/C(=O)O)C(=O)O)CC(C)(C)N1Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.39
DRD4 P21917 2/20 0.39
DRD3 P35462 2/20 0.39
TMEM97 Q5BJF2 2/20 0.39
SIGMAR1 Q99720 2/20 0.39
AMPD2 Q01433 3/20 0.39
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TSHR P16473 1/20 0.36
LMNA P02545 1/20 0.36
S1PR1 P21453 1/20 0.36
S1PR5 Q9H228 1/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
GAA P10253 1/20 0.35
GRM6 O15303 1/20 0.35
ELANE P08246 1/20 0.35
BRD4 O60885 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904601 1.00 DRD2 (0.39) DRD2DRD4DRD3TMEM97SIGMAR1
SCHEMBL9727745 0.86 TSHR (0.38) DRD2DRD4DRD3TMEM97SIGMAR1
SCHEMBL909995 0.82 AMPD2 (0.43) TMEM97SIGMAR1AMPD2MEN1KMT2A
SCHEMBL909996 0.82 AMPD2 (0.43) TMEM97SIGMAR1AMPD2MEN1KMT2A
SCHEMBL9514866 0.78 AMPD2 (0.40) DRD2DRD4DRD3AMPD2MEN1
SCHEMBL11841166 0.77 TSHR (0.43) DRD2DRD4DRD3TMEM97SIGMAR1
Acetic Acid SCHEMBL9813576 0.75 AMPD2 (0.47) TMEM97SIGMAR1AMPD2MEN1KMT2A
Crotonic Acid SCHEMBL10953476 0.74 MEN1 (0.41) DRD2DRD4DRD3SIGMAR1AMPD2
Crotonic Acid SCHEMBL9813584 0.74 MEN1 (0.41) DRD2DRD4DRD3SIGMAR1AMPD2
SCHEMBL39509 0.74 KMT2A (0.44) SIGMAR1AMPD2MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9829606-B2 Method of manufacturing hard coat film, hard coat film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-11-28 US disclosed
EP-2413697-B1 STABILISATION OF COMPOUNDS CONTAINING IODINE LANXESS DEUTSCHLAND GMBH (DE) 2017-11-08 EP disclosed
EP-2779830-B1 STABILIZATION OF COMPOUNDS CONTAINING IODINE HAVING POLYMERS COMPRISING NITROGEN LANXESS DEUTSCHLAND GMBH (DE) 2017-05-17 EP disclosed
US-20160124123-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY USING THE SAME FUJIFILM CORPORATION (JP) 2016-05-05 US disclosed
US-20150378062-A1 METHOD OF MANUFACTURING HARD COAT FILM, HARD COAT FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-31 US disclosed
US-8922889-B2 Cellulose acylate film, protective film for polarizing plate, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-12-30 US disclosed
EP-2594132-A1 Stabilisation of iodine containing compounds with polymers containing nitrogen Lanxess Deutschland GmbH (DE) 2013-05-22 EP disclosed
US-20130120839-A1 CELLULOSE ACYLATE FILM, PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-05-16 US disclosed
EP-2462805-A1 Formulations containing stabilised compounds containing iodine LANXESS Deutschland GmbH (DE) 2012-06-13 EP disclosed
EP-2449016-A1 POLYMERS CONTAINING HETEROCYCLIC 3-RING COMPOUNDS AND IODINE-CONTAINING COMPOUNDS Lanxess Deutschland GmbH (DE) 2012-05-09 EP disclosed
EP-0015230-B1 STABILIZED ORGANIC POLYMER COMPRISING 2-(2-HYDROXY-3,5-DI-TERT-OCTYLPHENYL)-2H-BENZOTRIAZOLE AS A LIGHT-STABILIZER CIBA-GEIGY AG (CH) 1983-02-23 EP disclosed
EP-0006213-B1 LIGHT STABILIZATION OF ACID CATALYSED STOVING ENAMELS CIBA-GEIGY AG (CH) 1982-09-01 EP disclosed
US-4315848-A PROTECTIVE COATING FOR AUTOMOBILES CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
US-4278589-A 2-[2-Hydroxy-3,5-di-(α,α-dimethylbenzyl)phenyl]-2H-benzotriazole and stabilized compositions CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
US-4278590-A AUTOMOBILE FINISHES CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
EP-0016723-A1 Light stabilisation of two-layer composite lacquers CIBA-GEIGY AG (CH) 1980-10-01 EP disclosed
EP-0015230-A1 Stabilized organic Polymer comprising 2-(2-hydroxy-3,5-di-tert-octylphenyl)-2H-benzotriazole as a light-stabilizer CIBA-GEIGY AG (CH) 1980-09-03 EP disclosed
EP-0006213-A1 Light stabilization of acid catalysed stoving enamels CIBA-GEIGY AG (CH) 1980-01-09 EP disclosed
EP-0006564-A2 2-(3.5-disubstituted-2-hydroxyphenyl)-2H-benzotriazoles and stabilized compositions containing them CIBA-GEIGY AG (CH) 1980-01-09 EP disclosed
EP-0002753-A2 Stabilisation of heat-curable metallic enamel paints against the action of light, humidity and oxygen by the addition of polyalkylpiperidine derivatives CIBA-GEIGY AG (CH) 1979-07-11 EP disclosed