Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | AMPD2 | Q01433 | 2/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6904601 | 0.86 | DRD2 (0.39) | TSHRKMT2AGAADRD2DRD4 | |
| SCHEMBL995046 | 0.86 | DRD2 (0.39) | TSHRKMT2AGAADRD2DRD4 | |
| SCHEMBL11841166 | 0.83 | TSHR (0.43) | TSHRKMT2AGAAHTTDRD2 | |
| SCHEMBL9229439 | 0.80 | TSHR (0.47) | TSHRKMT2AGAAHTTAMPD2 | |
| SCHEMBL315332 | 0.79 | TSHR (0.43) | TSHRKMT2AGAAHTTDRD2 | |
| SCHEMBL315331 | 0.79 | TSHR (0.43) | TSHRKMT2AGAAHTTDRD2 | |
| SCHEMBL1900036 | 0.79 | HCAR2 (0.43) | TSHRKMT2AGAAHTTDRD2 | |
| SCHEMBL1900033 | 0.79 | HCAR2 (0.43) | TSHRKMT2AGAAHTTDRD2 | |
| SCHEMBL11179317 | 0.78 | CHRM3 (0.43) | TSHRKMT2AGAAHTTAMPD2 | |
| SCHEMBL11403013 | 0.78 | TSHR (0.44) | TSHRKMT2AGAAHTTAMPD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5167844-A | Stabilized against thermal and oxidative degradation | CIBA-GEIGY CORPORATION (US) | 1992-12-01 | — | — | US | disclosed |