SCHEMBL9952034

SCHEMBL9952034

CCSc1ccccc1-c1nccn1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.47
HTR2C P28335 2/20 0.44
ADRA1D P25100 1/20 0.42
ADRA1A P35348 1/20 0.42
ADRA1B P35368 1/20 0.42
HTR2A P28223 1/20 0.42
NPC1 O15118 2/20 0.41
ATM Q13315 1/20 0.41
BCHE P06276 1/20 0.38
THRB P10828 1/20 0.38
ELANE P08246 1/20 0.36
MC4R P32245 1/20 0.36
KDM4E B2RXH2 3/20 0.36
HSD17B10 Q99714 2/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TP53 P04637 1/20 0.36
MAP2K7 O14733 1/20 0.36
S100A4 P26447 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9952063 0.81 FEN1 (0.39) BRD4HTR2CADRA1DADRA1AADRA1B
SCHEMBL19171596 0.79 BRD4 (0.54) BRD4HTR2CADRA1DADRA1AADRA1B
SCHEMBL9952864 0.78 HTR2C (0.37) BRD4HTR2CADRA1DADRA1AADRA1B
SCHEMBL9953820 0.77 HTR2C (0.36) BRD4HTR2CHTR2ANPC1KDM4E
SCHEMBL9952001 0.77 HTR2C (0.36) BRD4HTR2CADRA1DADRA1AADRA1B
SCHEMBL9951932 0.77 ALDH1A1 (0.38) BRD4HTR2CHTR2ANPC1THRB
SCHEMBL29755406 0.76 NPC1 (0.41) BRD4HTR2CNPC1KDM4EL3MBTL1
SCHEMBL18988970 0.76 NPC1 (0.41) BRD4HTR2CNPC1KDM4EL3MBTL1
Hydrochloric Acid SCHEMBL4345829 0.76 BRD4 (0.57) BRD4HTR2CADRA1DADRA1AADRA1B
SCHEMBL9822654 0.75 HTR2C (0.44) HTR2CNPC1ATMTHRBELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103261170-B Fused heterocyclic compounds and their use for pest control 住友化学株式会社 2016-08-24 CN disclosed
EP-2655337-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF Sumitomo Chemical Company Limited (JP) 2013-10-30 EP disclosed
WO-2012086848-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-06-28 WO disclosed