Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952034 | 0.81 | BRD4 (0.47) | HTR2CHTR2ANPC1ATMLMNA | |
| SCHEMBL9953585 | 0.78 | ALOX5AP (0.44) | FEN1ALOX5APHTR2CHDAC4HSD11B1 | |
| SCHEMBL9952060 | 0.74 | ALDH1A1 (0.40) | FEN1ALOX5APHTR2CHTR2ALMNA | |
| SCHEMBL12320192 | 0.72 | HDAC4 (0.43) | HDAC4BRD4CCNCCDK8NMT1 | |
| SCHEMBL14960634 | 0.70 | BRD4 (0.53) | HTR2CHDAC4HTR2AHSD11B1LMNA | |
| SCHEMBL28063013 | 0.70 | NPC1 (0.41) | HTR2CHDAC4NPC1BRD4CCNC | |
| SCHEMBL14960646 | 0.69 | TGFBR1 (0.50) | HDAC4CCNCCDK8 | |
| SCHEMBL9952864 | 0.67 | HTR2C (0.37) | HTR2CHTR2ANPC1LMNABRD4 | |
| SCHEMBL30958568 | 0.67 | NPC1 (0.47) | FEN1ALOX5APNPC1ATMLMNA | |
| SCHEMBL9952001 | 0.66 | HTR2C (0.36) | HTR2CHTR2ANPC1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655337-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | Sumitomo Chemical Company Limited (JP) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012086848-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-28 | — | — | WO | disclosed |