Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953820 | 0.84 | HTR2C (0.36) | HTR2CBRD4HTR2AALDH1A1RAB9A | |
| SCHEMBL9952001 | 0.84 | HTR2C (0.36) | HTR2CBRD4HTR2AALDH1A1RAB9A | |
| SCHEMBL9951932 | 0.84 | ALDH1A1 (0.38) | HTR2CBRD4HTR2AALDH1A1RAB9A | |
| SCHEMBL9952807 | 0.84 | HTR2C (0.34) | HTR2CBRD4HTR2AALDH1A1RAB9A | |
| SCHEMBL9952318 | 0.82 | ALDH1A1 (0.35) | HTR2CBRD4HTR2AALDH1A1RAB9A | |
| SCHEMBL9953333 | 0.79 | HTR2C (0.33) | HTR2CBRD4HTR2AALDH1A1RAB9A | |
| SCHEMBL9952034 | 0.78 | BRD4 (0.47) | HTR2CBRD4HTR2AALDH1A1KDM4E | |
| SCHEMBL9952060 | 0.76 | ALDH1A1 (0.40) | HTR2CHTR2AALDH1A1MAPTKDM4E | |
| SCHEMBL9953787 | 0.76 | PTPN1 (0.40) | HTR2CBRD4HTR2AALDH1A1RAB9A | |
| SCHEMBL9952936 | 0.71 | NPC1 (0.35) | HTR2CALDH1A1RAB9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655337-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | Sumitomo Chemical Company Limited (JP) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012086848-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-28 | — | — | WO | disclosed |