SCHEMBL9952189

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2653898	0.90	THRA (0.58)	SMN1; SMN2MAPTPRSS1CTSGCTRB1
	SCHEMBL14551257	0.83	PLK1 (0.57)	SMN1; SMN2MAPTPRSS1CTSGCTRB1
	SCHEMBL14120823	0.82	POLB (0.62)	SMN1; SMN2MAPTPRSS1CTSGCTRB1
	SCHEMBL2273935	0.82	PRSS1 (0.56)	SMN1; SMN2MAPTPRSS1CTSGCTRB1
	SCHEMBL11901025	0.82	PRSS1 (0.49)	SMN1; SMN2MAPTPRSS1CTSGCTRB1
	SCHEMBL2667533	0.81	LMNA (0.56)	SMN1; SMN2MAPTPRSS1CTSGCTRB1
	SCHEMBL27335124	0.81	PRSS1 (0.54)	SMN1; SMN2MAPTPRSS1CTSGCTRB1
	SCHEMBL5012300	0.80	PRSS1 (0.77)	SMN1; SMN2PRSS1CTSGCTRB1CMA1
	SCHEMBL2402293	0.80	PLK1 (0.53)	SMN1; SMN2MAPTPRSS1CTSGCTRB1
	SCHEMBL27941667	0.80	MAPT (0.61)	SMN1; SMN2MAPTPRSS1CTSGCTRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.