Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13958211 | 0.81 | RECQL (0.34) | MEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL2681973 | 0.81 | MEN1 (0.44) | ALDH1A1MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL7935850 | 0.81 | MEN1 (0.44) | ALDH1A1MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL2682079 | 0.81 | MEN1 (0.44) | ALDH1A1MEN1LMNAKMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL2680414 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MEN1LMNAKMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1504844 | 0.79 | KDM4E (0.36) | ALDH1A1MEN1LMNAKMT2AKDM4E | |
| SCHEMBL1503579 | 0.78 | NPSR1 (0.45) | ALDH1A1LMNAKMT2APOLBCYP3A4 | |
| SCHEMBL28794891 | 0.78 | ADAM17 (0.44) | ALDH1A1MEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL1503547 | 0.77 | ALDH1A1 (0.44) | ALDH1A1LMNAKMT2ACYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL2682302 | 0.77 | ALDH1A1 (0.44) | ALDH1A1LMNAKMT2ACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2801568-A1 | Benzene-sulphonamide compounds, method for synthesising and use in medicine and in cosmetics | Galderma Research & Development (FR) | 2014-11-12 | — | — | EP | disclosed |
| EP-2448920-B1 | Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine | GALDERMA RES & DEV (FR) | 2014-08-13 | — | — | EP | disclosed |
| EP-2448920-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | Galderma Research & Development (FR) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011001089-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-01-06 | — | — | WO | disclosed |