Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 5/20 | 0.42 |
| ▸ | CES1 | P23141 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28515537 | 0.81 | SLC6A2 (0.53) | SLC6A3SLC6A2PGRADRA2AADRA2B | |
| SCHEMBL9889372 | 0.77 | MAPT (0.58) | SLC6A3SLC6A2PGRADRA2AADRA2B | |
| SCHEMBL434807 | 0.77 | MDM2 (0.57) | SLC6A3SLC6A2PGRADRA2AADRA2B | |
| SCHEMBL9449408 | 0.76 | SLC6A2 (0.48) | SLC6A3SLC6A2PGRADRA2AADRA2B | |
| SCHEMBL11053944 | 0.76 | SLC6A2 (0.48) | SLC6A3SLC6A2PGRADRA2AADRA2B | |
| SCHEMBL3728429 | 0.76 | SLC6A2 (0.54) | SLC6A3SLC6A2PGRADRA2AADRA2B | |
| SCHEMBL17002137 | 0.76 | PGR (0.55) | SLC6A3SLC6A2PGRADRA2AADRA2B | |
| SCHEMBL517168 | 0.76 | MDM2 (0.55) | SLC6A3SLC6A2PGRADRA2AADRA2B | |
| SCHEMBL5702382 | 0.76 | SLC6A2 (0.54) | SLC6A3SLC6A2PGRADRA2AADRA2B | |
| SCHEMBL1824157 | 0.76 | PGR (0.55) | SLC6A3SLC6A2PGRADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655308-A1 | PROCESS FOR THE MANUFACTURE OF DIBENZOYLMETHANE DERIVATIVES | DSM IP Assets B.V. (NL) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012084770-A1 | PROCESS FOR THE MANUFACTURE OF DIBENZOYLMETHANE DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2012-06-28 | — | — | WO | disclosed |