SCHEMBL9889372

SCHEMBL9889372

CCCC(CCC)C(=O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.58
HTT P42858 2/20 0.58
RAB9A P51151 2/20 0.58
ATM Q13315 2/20 0.58
NPC1 O15118 2/20 0.58
MAPK1 P28482 1/20 0.58
SLC6A3 Q01959 2/20 0.56
SLC6A2 P23975 1/20 0.56
HTR2A P28223 2/20 0.52
HRH1 P35367 2/20 0.52
PGR P06401 1/20 0.52
ADRA2A P08913 1/20 0.52
ADRA2B P18089 1/20 0.52
KCNH2 Q12809 1/20 0.52
TDP1 Q9NUW8 2/20 0.48
HDAC1 Q13547 2/20 0.48
HDAC2 Q92769 2/20 0.48
CHRM1 P11229 1/20 0.48
AKR1A1 P14550 1/20 0.48
CHRM3 P20309 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12475390 0.93 MMP2 (0.52) MAPTHTTRAB9AATMNPC1
SCHEMBL1828579 0.92 MAPT (0.54) MAPTHTTRAB9AATMNPC1
SCHEMBL7714554 0.91 NPC1 (0.50) MAPTHTTRAB9AATMNPC1
SCHEMBL28770741 0.91 MMP2 (0.58) MAPTHTTRAB9AATMNPC1
SCHEMBL9390878 0.91 RAB9A (0.58) MAPTHTTRAB9AATMNPC1
SCHEMBL16466619 0.90 RAB9A (0.53) MAPTHTTRAB9AATMNPC1
SCHEMBL27992180 0.89 MMP2 (0.59) MAPTHTTRAB9AATMNPC1
SCHEMBL18658544 0.89 MAPK1 (0.51) MAPTHTTRAB9AATMNPC1
SCHEMBL12475594 0.88 MMP2 (0.55) MAPTHTTRAB9AATMNPC1
SCHEMBL9441153 0.87 RAB9A (0.50) MAPTHTTRAB9AATMNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160263236-A1 SHORT AND D-AMINO ACID-CONTAINING POLYPEPTIDES FOR THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC (CA) 2016-09-15 US disclosed
US-9161988-B2 Multimeric peptide conjugates and uses thereof ANGIOCHEM INC. (CA) 2015-10-20 US disclosed
EP-2673323-A2 COATING COMPOSITIONS FOR CONTAINERS AND OTHER ARTICLES AND METHODS OF COATING Valspar Sourcing, Inc. (US) 2013-12-18 EP disclosed
EP-2673326-A2 COATING COMPOSITIONS FOR CONTAINERS AND OTHER ARTICLES AND METHODS OF COATING Valspar Sourcing, Inc. (US) 2013-12-18 EP disclosed
US-20130280281-A1 SHORT AND D-AMINO ACID-CONTAINING POLYPEPTIDES FOR THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2013-10-24 US disclosed
WO-2012161758-A2 COATING COMPOSITIONS FOR CONTAINERS AND OTHER ARTICLES AND METHODS OF COATING VALSPAR SOURCING, INC. (US) 2012-11-29 WO disclosed
WO-2012109278-A2 COATING COMPOSITIONS FOR CONTAINERS AND OTHER ARTICLES AND METHODS OF COATING VALSPAR SOURCING, INC. (US) 2012-08-16 WO disclosed
US-20120141416-A1 MULTIMERIC PEPTIDE CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2012-06-07 US disclosed
US-20110021495-A1 QUINAZOLES USEFUL AS MODULATORS OF ION CHANNELS VERTEX PHARMACEUTICALS INCORPORATED (US) 2011-01-27 US disclosed
CN-101718964-A Substrate and protection layer for holograph recording medium and holograph recording medium TEIJIN CHEMICALS LTD 2010-06-02 CN disclosed
CN-101414120-A Film for gap layer of holograph recording medium and holograph recording medium TEIJIN CHEMICALS LTD (JP) 2009-04-22 CN disclosed
CN-100466079-C Hologram recording medium TOSHIBA KK (JP) 2009-03-04 CN disclosed
CN-101299130-A Substrate for holograph recording medium and holograph recording medium TEIJIN CHEMICALS LTD (JP) 2008-11-05 CN disclosed
CN-101295161-A Substrate for hologram recording medium and hologram recording medium TEIJIN CHEMICALS LTD (JP) 2008-10-29 CN disclosed
CN-101290470-A Base board for hologram recording medium and hologram recording medium TEIJIN CHEMICALS LTD (JP) 2008-10-22 CN disclosed
CN-101046674-A Holographic recording medium TOSHIBA KK (JP) 2007-10-03 CN disclosed
CN-1913009-A Holographic recording medium and holographic reproducing equipment TOKYO SHIBAURA ELECTRIC CO (JP) 2007-02-14 CN disclosed
CN-1815590-A Hologram recording medium TOKYO SHIBAURA ELECTRIC CO (JP) 2006-08-09 CN disclosed
CN-1199938-C Azine compound, process for preparation thereof, nematic liquid crystal composition and use in liquid crystal display system DAINIPPON INK & CHEMICALS (JP) 2005-05-04 CN disclosed
CN-1177592-A Azine compound, process for preparation thereof, nematic liquid crystal composition and use in liquid crystal display system DAINIPPON INK & CHEMICALS (JP) 1998-04-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120141416-A1 MULTIMERIC PEPTIDE CONJUGATES AND USES THEREOF LNPEP, DNPEP, VIP MAPT 207/4885HTT 58/4885RAB9A 1448/4885
US-20130280281-A1 SHORT AND D-AMINO ACID-CONTAINING POLYPEPTIDES FOR THERAPEUTIC CONJUGATES AND USES THEREOF SLC43A1, SLC7A5, DNPEP MAPT 316/4885HTT 113/4885RAB9A 290/4885
US-20110021495-A1 QUINAZOLES USEFUL AS MODULATORS OF ION CHANNELS KCNN3, CACNA1I, CACNA1B MAPT 1826/4885HTT 982/4885RAB9A 1388/4885
US-20160263236-A1 SHORT AND D-AMINO ACID-CONTAINING POLYPEPTIDES FOR THERAPEUTIC CONJUGATES AND USES THEREOF SLC43A1, SLC7A5, DNPEP MAPT 316/4885HTT 113/4885RAB9A 290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.