Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | BLM | P54132 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | GMNN | O75496 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014464 | 0.85 | GPR84 (0.35) | LMNASMN1; SMN2CYP1A2MAPK1MEN1 | |
| SCHEMBL2013997 | 0.81 | MEN1 (0.38) | LMNAGSRCYP1A2MEN1BLM | |
| SCHEMBL8277389 | 0.80 | — | — | |
| SCHEMBL7663032 | 0.80 | GSR (0.33) | LMNASMN1; SMN2GSRCYP1A2MEN1 | |
| SCHEMBL12754382 | 0.78 | AKR1B1 (0.36) | LMNAMEN1BLMKMT2AHIF1A | |
| SCHEMBL10104155 | 0.78 | AKR1B1 (0.36) | LMNAMEN1BLMKMT2AHIF1A | |
| SCHEMBL10119574 | 0.78 | AKR1B1 (0.36) | LMNAMEN1BLMKMT2AHIF1A | |
| SCHEMBL25620921 | 0.77 | — | — | |
| SCHEMBL2012234 | 0.75 | PTGS1 (0.38) | LMNASMN1; SMN2GSRCYP1A2MEN1 | |
| SCHEMBL14060689 | 0.73 | GSR (0.34) | GSRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2654455-B1 | USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS | DSM IP ASSETS BV (NL) | 2018-10-24 | — | — | EP | disclosed |
| US-9902685-B2 | Use of nitrooxy organic molecules in feed for reducing methane emission in ruminants, and/or to improve ruminant performance | DSM IP ASSETS B.V. (NL) | 2018-02-27 | — | — | US | disclosed |
| US-9266814-B2 | Use of nitrooxy organic molecules in feed for reducing methane emission in ruminants, and/or to improve ruminant performance | DSM IP ASSETS B.V. (NL) | 2016-02-23 | — | — | US | disclosed |
| US-20150376113-A1 | USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | DSM IP ASSETS BV (NL) | 2015-12-31 | — | — | US | disclosed |
| US-20140147529-A1 | USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | DSM IP ASSETS B.V. (NL) | 2014-05-29 | — | — | US | disclosed |
| EP-2654455-A1 | USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | DSM IP Assets B.V. (NL) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012084629-A1 | USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | DSM IP ASSETS B.V. (NL) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140147529-A1 | USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | MLNR, PIGS, MTR | LMNA 2045/4885SMN1; SMN2 2817/4885GSR 21/4885 |
| US-20150376113-A1 | USE OF NITROOXY ORGANIC MOLECULES IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | MLNR, PIGS, MTR | LMNA 2045/4885SMN1; SMN2 2817/4885GSR 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.