Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.42 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13036336 | 0.82 | SORT1 (0.52) | SORT1KCNK3KCNK9CNR1HDAC4 | |
| SCHEMBL15880285 | 0.82 | SORT1 (0.55) | SORT1KCNK3KCNK9CNR1HDAC4 | |
| SCHEMBL16377908 | 0.81 | SORT1 (0.52) | SORT1KCNK3KCNK9CNR1HDAC4 | |
| SCHEMBL19151039 | 0.81 | KMT2A (0.53) | SORT1KCNK3KCNK9CNR1HDAC4 | |
| SCHEMBL30930477 | 0.81 | SORT1 (0.51) | SORT1KCNK3KCNK9CNR1HDAC4 | |
| SCHEMBL20310370 | 0.81 | SORT1 (0.51) | SORT1KCNK3KCNK9CNR1HDAC4 | |
| SCHEMBL6383413 | 0.79 | SORT1 (0.50) | SORT1KCNK3KCNK9CNR1HDAC4 | |
| SCHEMBL19154013 | 0.79 | MTNR1B (0.56) | SORT1KCNK3KCNK9MEN1KMT2A | |
| SCHEMBL19308468 | 0.78 | KCNB1 (0.56) | SORT1KCNK3KCNK9CNR1HDAC4 | |
| SCHEMBL14920872 | 0.77 | SORT1 (0.48) | SORT1KCNK3KCNK9CNR1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103502237-A | FAAH inhibitors | IRONWOOD PHARMACEUTICALS INC | 2014-01-08 | — | — | CN | disclosed |
| EP-2655356-A1 | FAAH INHIBITORS | Ironwood Pharmaceuticals, Inc. (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012088469-A1 | FAAH INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2012-06-28 | — | — | WO | disclosed |