Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951942 | 0.83 | MAPT (0.47) | MALT1MAPTPOLBALDH1A1LMNA | |
| SCHEMBL31653962 | 0.78 | MEN1 (0.47) | POLBLMNAL3MBTL1GAAMEN1 | |
| SCHEMBL10153609 | 0.78 | MEN1 (0.47) | POLBLMNAL3MBTL1GAAMEN1 | |
| SCHEMBL9958675 | 0.76 | KMT2A (0.50) | MAPTPOLBALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9958635 | 0.76 | ALDH1A1 (0.50) | POLBALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL9959487 | 0.76 | HTT (0.43) | MAPTPOLBALDH1A1GLAGAA | |
| SCHEMBL14730468 | 0.74 | MALT1 (0.48) | MALT1MAPTALDH1A1LMNAGFER | |
| SCHEMBL19380274 | 0.73 | HDAC4 (0.44) | MAPTALDH1A1LMNAL3MBTL1GAA | |
| SCHEMBL19380301 | 0.73 | HDAC3 (0.40) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL10153606 | 0.72 | KCNA5 (0.48) | MAPTPOLBLMNAL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085003-A1 | 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONES AND RELATED COMPOUNDS USEFUL AS HIV REPLICATION INHIBITORS | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2012-06-28 | — | — | WO | claimed |
| WO-2012085003-A1 | 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONES AND RELATED COMPOUNDS USEFUL AS HIV REPLICATION INHIBITORS | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2012-06-28 | — | — | WO | disclosed |