Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4760887 | 0.75 | PPARA (0.48) | PPARACYP11B2CYP11B1KDM4ELRRK2 | |
| SCHEMBL13466167 | 0.74 | MEN1 (0.50) | PPARAPOLBMEN1KMT2AKDM4E | |
| SCHEMBL29930074 | 0.74 | MEN1 (0.50) | PPARAPOLBMEN1KMT2AKDM4E | |
| SCHEMBL24799621 | 0.74 | IDH1 (0.40) | PPARACYP11B2CYP11B1HTTRAB9A | |
| SCHEMBL30516056 | 0.74 | PPARA (0.40) | PPARAKMO | |
| SCHEMBL30516097 | 0.74 | MKNK1 (0.47) | PPARAPOLBHCAR2MEN1KMT2A | |
| SCHEMBL24921196 | 0.74 | CYP1A1 (0.46) | PPARACYP11B2CYP11B1RAB9A | |
| SCHEMBL29045049 | 0.74 | PPARA (0.40) | PPARAKMO | |
| SCHEMBL6265803 | 0.73 | PPARA (0.60) | CYP2A6PPARACYP11B2POLBMEN1 | |
| SCHEMBL30516092 | 0.73 | MKNK2 (0.49) | CYP2A6PPARACYP11B2HCAR2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |