SCHEMBL30516056

SCHEMBL30516056

O=Cc1cncc(-c2ncon2)c1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 1/20 0.40
KMO O15229 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29045049 1.00 PPARA (0.40) PPARAKMO
Hydrochloric Acid SCHEMBL30516112 0.98 PPARA (0.39) PPARAKMO
SCHEMBL1175073 0.77 BRD4 (0.48) PPARA
SCHEMBL29955861 0.77 BRD4 (0.48) PPARA
SCHEMBL31180051 0.75 PTGS2 (0.38)
SCHEMBL1356430 0.75 PTGS2 (0.38)
SCHEMBL6851712 0.75 BRD4 (0.42) PPARAKMO
SCHEMBL9952822 0.74 PTK2 (0.46) PPARAKMO
SCHEMBL30516097 0.73 MKNK1 (0.47) PPARAKMO
SCHEMBL30516092 0.72 MKNK2 (0.49) PPARAKMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116514790-A Tri-aromatic heterocyclic piperazine small molecular organic compound targeting STAT3 and application thereof 华东师范大学 2023-08-01 CN claimed
CN-116514790-A Tri-aromatic heterocyclic piperazine small molecular organic compound targeting STAT3 and application thereof 华东师范大学 2023-08-01 CN disclosed