Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30918933 | 0.81 | LMNA (0.53) | LMNAHPGDPTGESJAK2GSK3A | |
| SCHEMBL30988528 | 0.81 | TYMS (0.51) | LMNAHPGDPTGESJAK2GSK3A | |
| SCHEMBL6667192 | 0.81 | LMNA (0.56) | LMNAHPGDJAK2GSK3AGSK3B | |
| SCHEMBL578429 | 0.79 | KDM4E (0.50) | LMNAHPGDCHUKMAPK1ALDH1A1 | |
| SCHEMBL5789983 | 0.79 | TYMS (0.39) | LMNAJAK2GSK3AGSK3BCHEK1 | |
| SCHEMBL3862742 | 0.77 | LMNA (0.47) | LMNAHPGDJAK2GSK3AGSK3B | |
| SCHEMBL22101352 | 0.77 | PRNP (0.48) | LMNAHPGDJAK2GSK3AGSK3B | |
| SCHEMBL3497007 | 0.76 | RXFP1 (0.69) | LMNAHPGDPTGESPRKD3MAP4K4 | |
| SCHEMBL1192650 | 0.76 | NOS1 (0.41) | LMNAPTGESJAK2DYRK1ACHUK | |
| SCHEMBL6616116 | 0.75 | RPS6KA3 (0.50) | LMNAHPGDJAK2GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |