Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | PAK4 | O96013 | 2/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667192 | 0.79 | LMNA (0.56) | PRNPCYP1A2CYP2C9CYP2C19PPARG | |
| SCHEMBL582347 | 0.79 | RAB9A (0.49) | CYP1A2RXFP1GSK3BNTRK1PIM1 | |
| SCHEMBL9384223 | 0.77 | DDAH1 (0.58) | CYP1A2CYP2C19LMNAHPGDSMN1; SMN2 | |
| SCHEMBL9952845 | 0.77 | LMNA (0.49) | RXFP1LMNAHPGDHAVCR2MAPK1 | |
| SCHEMBL12350646 | 0.77 | DDAH1 (0.58) | PRNPCYP1A2CYP2C9CYP2C19PPARG | |
| SCHEMBL9143559 | 0.77 | CA12 (0.51) | NPSR1LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL15832250 | 0.76 | F10 (0.48) | — | |
| SCHEMBL30988528 | 0.76 | TYMS (0.51) | RXFP1LMNAHPGDHAVCR2MAPK1 | |
| SCHEMBL3862742 | 0.75 | LMNA (0.47) | PRNPCYP1A2CYP2C9CYP2C19PPARG | |
| SCHEMBL17298090 | 0.75 | TNKS2 (0.62) | PRNPCYP1A2CYP2C9CYP2C19PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |