Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL996065 | 0.91 | MAPK1 (0.49) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL995866 | 0.89 | PPARD (0.50) | ALDH1A1KMT2AMEN1KDM4EFAAH | |
| SCHEMBL16054123 | 0.82 | ALDH1A1 (0.36) | ALDH1A1KMT2AMEN1LMNAKDM4E | |
| SCHEMBL16054684 | 0.75 | ACHE (0.38) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1000038 | 0.75 | SMN1; SMN2 (0.49) | ALDH1A1KMT2ALMNANPC1RAB9A | |
| SCHEMBL995978 | 0.74 | TDP1 (0.41) | ALDH1A1KMT2ALMNAKDM4ENPC1 | |
| SCHEMBL995318 | 0.74 | MEN1 (0.45) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL16054820 | 0.73 | HRH2 (0.40) | ALDH1A1KMT2ALMNAKDM4ENPC1 | |
| SCHEMBL995317 | 0.73 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL996323 | 0.70 | EPHX2 (0.34) | ALDH1A1KMT2ANPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448920-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | Galderma Research & Development (FR) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011001089-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-01-06 | — | — | WO | disclosed |