Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL996067 | 0.91 | MAPK1 (0.49) | ALDH1A1ATMLMNARAB9AMEN1 | |
| SCHEMBL995867 | 0.88 | L3MBTL1 (0.47) | ALDH1A1MEN1KMT2AFAAHCACNA1G | |
| SCHEMBL16054124 | 0.82 | KDM4E (0.39) | ALDH1A1LMNARAB9AKMT2ANPC1 | |
| SCHEMBL995318 | 0.78 | MEN1 (0.45) | ALDH1A1ATMLMNARAB9AMEN1 | |
| SCHEMBL16054933 | 0.75 | HRH2 (0.41) | ALDH1A1LMNARAB9AKMT2ANPC1 | |
| SCHEMBL1000039 | 0.75 | SMN1; SMN2 (0.49) | ALDH1A1LMNARAB9AKMT2ANPC1 | |
| SCHEMBL16054685 | 0.75 | SIGMAR1 (0.38) | RAB9AKMT2ANPC1TP53HPGD | |
| SCHEMBL995979 | 0.74 | TDP1 (0.41) | ALDH1A1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL995315 | 0.73 | ALDH1A1 (0.44) | ALDH1A1ATMLMNARAB9AMEN1 | |
| SCHEMBL996324 | 0.72 | EPHX2 (0.35) | ALDH1A1LMNARAB9AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448920-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | Galderma Research & Development (FR) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011001089-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-01-06 | — | — | WO | disclosed |