Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | IDH2 | P48735 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL856252 | 0.83 | PLA2G1B (0.62) | PLA2G1BATG4BMEN1KMT2AGAA | |
| SCHEMBL9954303 | 0.80 | PLA2G1B (0.41) | ALPLPLA2G1BATG4BPIK3CDPIK3CA | |
| SCHEMBL16926889 | 0.78 | ALPL (0.47) | ALPLMEN1KMT2AGAALMNA | |
| SCHEMBL15646656 | 0.77 | ALDH1A1 (0.55) | KMT2AGAALMNAMAPTIDH2 | |
| SCHEMBL21494353 | 0.75 | ALPL (0.52) | ALPLPLA2G1BATG4BMEN1KMT2A | |
| SCHEMBL18633957 | 0.75 | ALPL (0.44) | ALPLPLA2G1BATG4BMEN1KMT2A | |
| SCHEMBL15054564 | 0.74 | PIK3CD (0.38) | ALPLPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL14093070 | 0.72 | KMT2A (0.36) | PIK3CDPIK3CAPIK3CBPIK3CGMEN1 | |
| SCHEMBL789628 | 0.71 | ALPL (0.47) | ALPLPLA2G1BATG4BMEN1KMT2A | |
| SCHEMBL16926583 | 0.70 | CDK1 (0.60) | ALPLPLA2G1BATG4BPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |