Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | IDH2 | P48735 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15053855 | 0.84 | SMN1; SMN2 (0.49) | ALPLSLC22A12CA1CA2GLA | |
| SCHEMBL15053983 | 0.81 | POLB (0.43) | GLASMN1; SMN2 | |
| SCHEMBL15054645 | 0.81 | CA1 (0.44) | ALPLCA1CA2GLASMN1; SMN2 | |
| SCHEMBL15054144 | 0.80 | ALDH1A1 (0.43) | ALPLSLC22A12PPARGGRM5PTGES | |
| SCHEMBL25408105 | 0.80 | NPY5R (0.44) | ADRA2ANPY5RMCHR1 | |
| SCHEMBL15055023 | 0.80 | LMNA (0.53) | GLASMN1; SMN2 | |
| SCHEMBL15054694 | 0.80 | GAA (0.54) | — | |
| SCHEMBL15054127 | 0.79 | PTGES (0.38) | ALPLSLC22A12PPARGGRM5PTGES | |
| SCHEMBL15054129 | 0.79 | POLB (0.45) | GLASMN1; SMN2 | |
| SCHEMBL15054085 | 0.76 | SMN1; SMN2 (0.36) | ALPLSLC22A12PPARGCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096153-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2013-06-27 | — | — | WO | disclosed |