Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6780126 | 0.84 | NPC1 (0.57) | CYP3A4MEN1CYP1A2GAACYP2C9 | |
| SCHEMBL8393246 | 0.80 | NPC1 (0.64) | CYP3A4MEN1CYP1A2GAACYP2C9 | |
| SCHEMBL29001248 | 0.79 | NPC1 (0.52) | CYP3A4CYP1A2CYP2C19KMT2ATSHR | |
| SCHEMBL15269110 | 0.79 | NPC1 (0.67) | CYP3A4MEN1CYP1A2GAACYP2C9 | |
| SCHEMBL15271897 | 0.79 | NPC1 (0.67) | CYP3A4MEN1CYP1A2GAACYP2C9 | |
| SCHEMBL15269042 | 0.79 | NPC1 (0.67) | CYP3A4MEN1CYP1A2GAACYP2C9 | |
| SCHEMBL8393232 | 0.79 | NPC1 (0.67) | CYP3A4MEN1CYP1A2GAACYP2C9 | |
| SCHEMBL997440 | 0.78 | ALDH1A1 (0.42) | CYP3A4MEN1CYP1A2GAACYP2C9 | |
| SCHEMBL11136621 | 0.76 | DRD2 (0.46) | CYP3A4GAAKMT2ATSHRNPC1 | |
| SCHEMBL4456605 | 0.76 | SMN1; SMN2 (0.52) | CYP3A4MEN1CYP1A2GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809574-B2 | Method for preparing isocyanates by liquid-phase thermal cracking | LANZHOU INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2014-08-19 | — | — | US | disclosed |
| US-20110021810-A1 | METHOD FOR PREPARING ISOCYANATES BY LIQUID-PHASE THERMAL CRACKING | LANZHOU INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021810-A1 | METHOD FOR PREPARING ISOCYANATES BY LIQUID-PHASE THERMAL CRACKING | DBI, CCNI, DGKI | CYP3A4 2485/4885MEN1 4044/4885CYP1A2 2620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.