Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10277403 | 0.89 | ALPL (0.71) | ALPLSMN1; SMN2ALDH1A1PKMTSHR | |
| SCHEMBL798532 | 0.89 | ALPL (0.68) | ALPLSMN1; SMN2NPSR1ALDH1A1KMT2A | |
| SCHEMBL9952780 | 0.89 | ALPL (0.68) | ALPLSMN1; SMN2NPSR1ALDH1A1KMT2A | |
| SCHEMBL798423 | 0.89 | ALPL (0.76) | ALPLALDH1A1KMT2APIK3CDPIK3R1 | |
| SCHEMBL24457985 | 0.88 | ALPL (0.59) | ALPLSMN1; SMN2NPSR1ALDH1A1EGFR | |
| SCHEMBL9953749 | 0.88 | ALPL (0.67) | ALPLSMN1; SMN2ALDH1A1PKMKMT2A | |
| SCHEMBL9953632 | 0.85 | ALPL (0.66) | ALPLSMN1; SMN2ALDH1A1KMT2APIK3CD | |
| SCHEMBL10277379 | 0.83 | ALPL (0.69) | ALPLSMN1; SMN2ALDH1A1TSHRPIK3CD | |
| SCHEMBL798326 | 0.83 | ALPL (0.69) | ALPLSMN1; SMN2ALDH1A1KMT2APIK3CD | |
| SCHEMBL9954577 | 0.83 | ALPL (0.66) | ALPLSMN1; SMN2ALDH1A1KMT2APIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |