Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 13/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954515 | 0.88 | PI4KA (0.57) | PI4KAPIK3CGCYP11B2CYP11B1 | |
| SCHEMBL9954015 | 0.86 | PI4KA (0.51) | PI4KAPIK3CG | |
| SCHEMBL9959815 | 0.86 | XDH (0.56) | PI4KAPIK3CG | |
| SCHEMBL10288698 | 0.85 | PI4KA (0.59) | PI4KAPIK3CG | |
| SCHEMBL9954693 | 0.83 | PIM1 (0.46) | PI4KAPIK3CGCYP11B2 | |
| SCHEMBL10289054 | 0.83 | PI4KA (0.51) | PI4KAPIK3CG | |
| SCHEMBL9954049 | 0.83 | PI4KA (0.53) | PI4KAPIK3CGHCAR1 | |
| SCHEMBL10288780 | 0.83 | PI4KA (0.52) | PI4KAPIK3CGHCAR1TGM2 | |
| SCHEMBL10289377 | 0.82 | PI4KA (0.49) | PI4KAPIK3CG | |
| SCHEMBL9955619 | 0.80 | PI4KA (0.56) | PI4KAPIK3CGCYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |