Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | PI4KA | P42356 | 7/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | CTSA | P10619 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953679 | 0.83 | PI4KA (0.51) | PI4KAPIK3CGCYP11B2 | |
| SCHEMBL14247526 | 0.81 | CYP11B2 (0.44) | PIM1PIM3PIM2HPGDJAK2 | |
| SCHEMBL9954515 | 0.80 | PI4KA (0.57) | PI4KAPIK3CGCYP11B2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10289377 | 0.79 | PI4KA (0.49) | PI4KAPIK3CG | |
| SCHEMBL9954015 | 0.79 | PI4KA (0.51) | PI4KAPIK3CGJAK2 | |
| SCHEMBL9959815 | 0.79 | XDH (0.56) | PI4KAPIK3CG | |
| SCHEMBL10288698 | 0.78 | PI4KA (0.59) | PI4KAPIK3CG | |
| SCHEMBL9952593 | 0.77 | PI4KA (0.47) | PI4KAPIK3CGCYP11B2 | |
| SCHEMBL10289054 | 0.76 | PI4KA (0.51) | PI4KAPIK3CGALDH1A1CYP1A2 | |
| SCHEMBL9953028 | 0.76 | PI4KA (0.50) | PI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |