Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 16/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.59 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10289377 | 0.87 | PI4KA (0.49) | PI4KAPIK3CG | |
| SCHEMBL9959815 | 0.86 | XDH (0.56) | PI4KAPIK3CGXDH | |
| SCHEMBL9954015 | 0.86 | PI4KA (0.51) | PI4KAPIK3CGXDH | |
| SCHEMBL9954515 | 0.85 | PI4KA (0.57) | PI4KAPIK3CG | |
| SCHEMBL9953679 | 0.85 | PI4KA (0.51) | PI4KAPIK3CG | |
| SCHEMBL10289054 | 0.83 | PI4KA (0.51) | PI4KAPIK3CGXDH | |
| SCHEMBL9953943 | 0.82 | PI4KA (0.59) | PI4KAPIK3CG | |
| SCHEMBL10289075 | 0.81 | PI4KA (0.77) | PI4KAPIK3CG | |
| SCHEMBL9954428 | 0.79 | PI4KA (0.56) | PI4KAPIK3CG | |
| SCHEMBL9954693 | 0.78 | PIM1 (0.46) | PI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |