Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954053 | 0.79 | ALPL (0.38) | ALPLAAK1PDGFRBKDRDGAT1 | |
| SCHEMBL9954735 | 0.78 | ALPL (0.33) | ALPLAAK1 | |
| SCHEMBL3668559 | 0.75 | ALPL (0.46) | ALPLAAK1PDGFRBKDRDGAT1 | |
| SCHEMBL29504617 | 0.75 | ALPL (0.46) | ALPLAAK1PDGFRBKDRDGAT1 | |
| SCHEMBL9952722 | 0.74 | HIF1A (0.40) | SMN1; SMN2LRRK2ALDH1A1 | |
| SCHEMBL3220509 | 0.74 | DGAT1 (0.44) | SMN1; SMN2DGAT1IRAK4 | |
| SCHEMBL10289150 | 0.72 | ALPL (0.39) | ALPLAAK1PDGFRBKDRALDH1A1 | |
| SCHEMBL29555798 | 0.72 | ALPL (0.46) | ALPLAAK1PDGFRBKDRDGAT1 | |
| SCHEMBL407919 | 0.72 | ALPL (0.46) | ALPLAAK1PDGFRBKDRDGAT1 | |
| SCHEMBL9953913 | 0.72 | ALPL (0.40) | ALPLAAK1PDGFRBKDRDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |