Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952972 | 0.79 | ALPL (0.33) | ALPLAAK1PDGFRBKDRDGAT1 | |
| SCHEMBL9953699 | 0.79 | ALPL (0.38) | ALPLAAK1PDGFRBKDRDGAT1 | |
| SCHEMBL31267052 | 0.78 | LPL (0.33) | RAB9ANPC1TYK2 | |
| SCHEMBL10289150 | 0.77 | ALPL (0.39) | ALPLAAK1PDGFRBKDRKDM4E | |
| SCHEMBL30036821 | 0.77 | ALPL (0.39) | ALPLAAK1RAB9ANPC1PDGFRB | |
| SCHEMBL28575518 | 0.77 | ALPL (0.39) | ALPLAAK1RAB9ANPC1PDGFRB | |
| SCHEMBL9953913 | 0.77 | ALPL (0.40) | ALPLAAK1PDGFRBKDRDGAT1 | |
| SCHEMBL9954260 | 0.74 | RAB9A (0.38) | RAB9ANPC1EPHX2PPARAPDE10A | |
| SCHEMBL29406802 | 0.74 | DGAT1 (0.44) | PPARADGAT1 | |
| SCHEMBL30023285 | 0.74 | PPARA (0.40) | EPHX2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |