Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 14/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14764171 | 0.85 | CNR2 (0.35) | CNR2OPRK1NPC1RAB9AALDH1A1 | |
| SCHEMBL757419 | 0.78 | OPRK1 (0.49) | OPRK1HSD17B10 | |
| SCHEMBL29457453 | 0.78 | OPRK1 (0.49) | OPRK1HSD17B10 | |
| SCHEMBL14764185 | 0.76 | HTT (0.44) | CNR2OPRK1HSD17B10PIK3C3NPC1 | |
| SCHEMBL316314 | 0.76 | HSD17B10 (0.50) | CNR2OPRK1HSD17B10ALDH1A1 | |
| SCHEMBL29527502 | 0.75 | OPRK1 (0.44) | CNR2OPRK1HSD17B10NPC1RAB9A | |
| SCHEMBL839912 | 0.75 | OPRK1 (0.44) | CNR2OPRK1HSD17B10NPC1RAB9A | |
| SCHEMBL11875941 | 0.75 | CNR2 (0.38) | CNR2OPRK1HSD17B10NPC1RAB9A | |
| SCHEMBL9953358 | 0.75 | ALDH1A1 (0.38) | CNR2OPRK1ALDH1A1MAPTAURKA | |
| Lithium SCHEMBL9954426 | 0.75 | HSD17B10 (0.49) | CNR2OPRK1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |