Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316314 | 0.98 | HSD17B10 (0.50) | HSD17B10LCKFYNPOLBTDP1 | |
| SCHEMBL9954416 | 0.97 | HSD17B10 (0.49) | HSD17B10LCKFYNPOLBTDP1 | |
| SCHEMBL31182069 | 0.87 | HSD17B10 (0.42) | HSD17B10LCKFYNPOLBKDM4E | |
| SCHEMBL14764185 | 0.84 | HTT (0.44) | HSD17B10ALDH1A1CNR2HPGDOPRK1 | |
| SCHEMBL8125788 | 0.83 | NNMT (0.46) | HSD17B10POLBKDM4EALDH1A1CNR2 | |
| SCHEMBL11875941 | 0.83 | CNR2 (0.38) | HSD17B10CNR2OPRK1 | |
| SCHEMBL29457453 | 0.83 | OPRK1 (0.49) | HSD17B10OPRK1 | |
| SCHEMBL757419 | 0.83 | OPRK1 (0.49) | HSD17B10OPRK1 | |
| SCHEMBL1994955 | 0.82 | ALDH1A1 (0.44) | HSD17B10POLBKDM4EALDH1A1AKR1C3 | |
| Lithium Ion SCHEMBL9954420 | 0.81 | CNR2 (0.37) | HSD17B10CNR2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |