Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15427733 | 0.72 | AOC3 (0.39) | AOC3HTR2AKDM4EHSD17B10MEN1 | |
| SCHEMBL19585465 | 0.72 | SLC6A4 (0.37) | AOC3HTR2AKDM4EHSD17B10MEN1 | |
| SCHEMBL18386259 | 0.70 | ALDH1A1 (0.50) | AOC3KDM4EHSD17B10MEN1ALDH1A1 | |
| SCHEMBL9953477 | 0.69 | MEN1 (0.48) | KDM4EMEN1ALDH1A1MAPTPKM | |
| SCHEMBL6863388 | 0.68 | KMT2A (0.54) | KDM4EHSD17B10MEN1ALDH1A1GAA | |
| SCHEMBL6906228 | 0.68 | AOC3 (0.35) | AOC3HTR2AKDM4EHSD17B10 | |
| SCHEMBL202164 | 0.67 | AR (0.55) | — | |
| SCHEMBL8535525 | 0.67 | PTK2 (0.41) | PTK2 | |
| SCHEMBL28716249 | 0.66 | NPC1 (0.41) | PTK2HSD17B10MEN1ALDH1A1GAA | |
| SCHEMBL18353018 | 0.64 | CYP3A4 (0.52) | AOC3KDM4EHSD17B10MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012088184-A1 | INTEGRATED PROCESSES FOR THE PREPARATION OF HETEROCYCLIC AROMATIC POLYMER PRECURSORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | claimed |
| WO-2012088182-A2 | 2,4,5-TRIAMINOTHIOPHENOLS AND RELATED COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012088184-A1 | INTEGRATED PROCESSES FOR THE PREPARATION OF HETEROCYCLIC AROMATIC POLYMER PRECURSORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012088184-A1 | INTEGRATED PROCESSES FOR THE PREPARATION OF HETEROCYCLIC AROMATIC POLYMER PRECURSORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |