Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 11/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31241091 | 0.89 | CACNA2D1 (0.47) | CACNA2D1MEN1KMT2AOPRM1ATM | |
| SCHEMBL9952969 | 0.85 | DPP4 (0.51) | CACNA2D1MEN1KMT2AOPRM1ATM | |
| SCHEMBL8351697 | 0.84 | MEN1 (0.54) | CACNA2D1MEN1KMT2AOPRM1ATM | |
| SCHEMBL9953325 | 0.82 | HSD17B10 (0.49) | MEN1KMT2AATMMAPTCYP1A2 | |
| SCHEMBL31241110 | 0.81 | PDE5A (0.46) | CACNA2D1MEN1KMT2AATMHTT | |
| SCHEMBL9953300 | 0.81 | PDE5A (0.46) | CACNA2D1MEN1KMT2AATMHTT | |
| SCHEMBL9954631 | 0.80 | KMT2A (0.46) | MEN1KMT2AATMMAPTCYP1A2 | |
| SCHEMBL9954332 | 0.78 | PTGS2 (0.45) | CACNA2D1MEN1KMT2AATM | |
| SCHEMBL10819474 | 0.77 | ACSS2 (0.47) | MAPTCYP1A2CYP2D6HTTTP53 | |
| SCHEMBL9953464 | 0.77 | ALDH1A1 (0.57) | MEN1KMT2AATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |