Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.35 |
| ▸ | S100A9 | P06702 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954692 | 0.80 | SHMT2 (0.42) | SHMT2MEN1KMT2APOLBALPL | |
| SCHEMBL9953641 | 0.80 | SHMT2 (0.44) | SHMT2MEN1KMT2APOLBALPL | |
| SCHEMBL9955406 | 0.77 | GLA (0.42) | SHMT2MEN1KMT2APOLBALPL | |
| SCHEMBL20680333 | 0.76 | SHMT2 (0.40) | SHMT2MEN1KMT2APOLBALPL | |
| SCHEMBL14305923 | 0.76 | SMN1; SMN2 (0.57) | SHMT2MEN1KMT2APOLBALPL | |
| SCHEMBL9952694 | 0.76 | NPSR1 (0.46) | SHMT2MEN1KMT2APOLBALPL | |
| SCHEMBL10288904 | 0.76 | ALPL (0.56) | ALPLPIK3C3AAK1 | |
| SCHEMBL14305925 | 0.76 | SHMT2 (0.39) | SHMT2MEN1KMT2APOLBALPL | |
| SCHEMBL14305922 | 0.76 | SHMT2 (0.39) | SHMT2MEN1KMT2APOLBALPL | |
| SCHEMBL10289140 | 0.76 | KMT2A (0.44) | SHMT2MEN1KMT2AKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |