Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | CCR4 | P51679 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14305922 | 0.86 | SHMT2 (0.39) | SHMT2MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL14247692 | 0.85 | MEN1 (0.42) | SHMT2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9953641 | 0.84 | SHMT2 (0.44) | SHMT2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL16007223 | 0.84 | ALDH1A1 (0.38) | SHMT2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL16007312 | 0.81 | LRRK2 (0.42) | SHMT2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9955406 | 0.81 | GLA (0.42) | SHMT2MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL14305923 | 0.81 | SMN1; SMN2 (0.57) | SHMT2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9952694 | 0.81 | NPSR1 (0.46) | SHMT2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9954056 | 0.80 | SHMT2 (0.39) | SHMT2MEN1KMT2APOLBPIK3C3 | |
| SCHEMBL14305925 | 0.80 | SHMT2 (0.39) | SHMT2MEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |