Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.71 |
| ▸ | NPC1 | O15118 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954640 | 0.86 | RAB9A (0.73) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9954835 | 0.84 | TSHR (0.68) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL31241075 | 0.83 | RAB9A (0.74) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL31241072 | 0.80 | RAB9A (1.00) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL16528767 | 0.77 | SMN1; SMN2 (0.53) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL10020286 | 0.77 | MDM2 (1.00) | RAB9AMAPTLMNAMDM2SMN1; SMN2 | |
| SCHEMBL16166784 | 0.77 | RAB9A (0.61) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9027737 | 0.77 | RAB9A (0.60) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL10289060 | 0.76 | RAB9A (0.56) | RAB9ANPC1MAPTLMNASMN1; SMN2 | |
| SCHEMBL16879078 | 0.76 | MEN1 (0.72) | RAB9ANPC1LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |