Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 9/20 | 0.62 |
| ▸ | NPC1 | O15118 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | FPR2 | P25090 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954640 | 0.85 | RAB9A (0.73) | TSHRRAB9ANPC1MEN1KMT2A | |
| SCHEMBL9954182 | 0.84 | RAB9A (0.71) | TSHRRAB9ANPC1MEN1KMT2A | |
| SCHEMBL22926672 | 0.83 | FPR2 (0.74) | RAB9ANPC1MEN1KMT2AHTT | |
| SCHEMBL29517932 | 0.83 | FPR2 (0.74) | RAB9ANPC1MEN1KMT2AHTT | |
| SCHEMBL9637653 | 0.81 | MEN1 (0.77) | TSHRRAB9ANPC1MEN1KMT2A | |
| SCHEMBL30051982 | 0.81 | MEN1 (0.77) | TSHRRAB9ANPC1MEN1KMT2A | |
| Bromide SCHEMBL29417998 | 0.79 | MEN1 (0.74) | TSHRRAB9ANPC1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29388210 | 0.79 | MEN1 (0.74) | TSHRRAB9ANPC1MEN1KMT2A | |
| SCHEMBL20172471 | 0.79 | NPC1 (0.47) | RAB9ANPC1MEN1KMT2AHTT | |
| SCHEMBL31241036 | 0.78 | RAB9A (0.71) | RAB9ANPC1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |