Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.73 |
| ▸ | NPC1 | O15118 | 9/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | PIM1 | P11309 | 1/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | FLT3 | P36888 | 1/20 | 0.61 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.61 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954182 | 0.86 | RAB9A (0.71) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9954835 | 0.85 | TSHR (0.68) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31241075 | 0.84 | RAB9A (0.74) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31241036 | 0.83 | RAB9A (0.71) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31241072 | 0.81 | RAB9A (1.00) | RAB9ANPC1MAPTSMN1; SMN2LMNA | |
| SCHEMBL1018755 | 0.81 | HCAR3 (0.69) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27578720 | 0.81 | L3MBTL1 (0.77) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27581139 | 0.81 | RAB9A (0.73) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28513546 | 0.81 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2ADORA3PIM1 | |
| SCHEMBL3461453 | 0.81 | RAB9A (0.62) | RAB9ANPC1MAPTSMN1; SMN2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812505-A | PI5P4K gamma inhibitor compound, pharmaceutical composition, and preparation method and application thereof | 贵州医科大学 | 2024-10-22 | — | — | CN | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |