Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 16/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.47 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953702 | 0.80 | PI4KA (0.48) | PI4KAPIK3CGHCAR1 | |
| SCHEMBL9953028 | 0.78 | PI4KA (0.50) | PI4KAPIK3CGHCAR1 | |
| SCHEMBL9954049 | 0.78 | PI4KA (0.53) | PI4KAPIK3CGHCAR1MAPT | |
| SCHEMBL10289152 | 0.77 | PI4KA (0.48) | PI4KAPIK3CGHCAR1 | |
| SCHEMBL9955619 | 0.76 | PI4KA (0.56) | PI4KAPIK3CG | |
| SCHEMBL9954428 | 0.76 | PI4KA (0.56) | PI4KAPIK3CG | |
| SCHEMBL9953679 | 0.76 | PI4KA (0.51) | PI4KAPIK3CGHCAR1 | |
| SCHEMBL10288780 | 0.76 | PI4KA (0.52) | PI4KAPIK3CGHCAR1MAPT | |
| SCHEMBL10288787 | 0.75 | PI4KA (0.50) | PI4KAPIK3CGHCAR1ALDH1A1HPGD | |
| SCHEMBL9953943 | 0.75 | PI4KA (0.59) | PI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |