Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 15/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.50 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL9954566 | 0.95 | PI4KA (0.47) | PI4KAPIK3CGHCAR1CYP11B1CYP11B2 | |
| SCHEMBL9954049 | 0.82 | PI4KA (0.53) | PI4KAPIK3CGHCAR1MEN1KMT2A | |
| SCHEMBL9952593 | 0.82 | PI4KA (0.47) | PI4KAPIK3CGHCAR1CYP11B2 | |
| SCHEMBL10288780 | 0.80 | PI4KA (0.52) | PI4KAPIK3CGHCAR1 | |
| SCHEMBL9954428 | 0.80 | PI4KA (0.56) | PI4KAPIK3CG | |
| SCHEMBL9955619 | 0.80 | PI4KA (0.56) | PI4KAPIK3CGCYP11B1CYP11B2 | |
| SCHEMBL9953679 | 0.80 | PI4KA (0.51) | PI4KAPIK3CGHCAR1CYP11B1CYP11B2 | |
| SCHEMBL9953943 | 0.79 | PI4KA (0.59) | PI4KAPIK3CG | |
| Formic Acid SCHEMBL9954795 | 0.78 | PI4KA (0.44) | PI4KAPIK3CGCYP11B2 | |
| SCHEMBL9953702 | 0.76 | PI4KA (0.48) | PI4KAPIK3CGHCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |