Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | BRS3 | P32247 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953667 | 0.81 | PIK3C3 (0.42) | CA1CA2ALOX5APFEN1MEN1 | |
| SCHEMBL9954020 | 0.78 | PIK3C3 (0.49) | ALDH1A1SMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL14305926 | 0.76 | PIK3C3 (0.55) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL9954686 | 0.76 | PIK3C3 (0.53) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL9953075 | 0.75 | PIK3C3 (0.52) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL15915670 | 0.74 | CA1 (0.60) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL15915716 | 0.74 | CA1 (0.60) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL21760960 | 0.73 | PIK3C2G (0.48) | ALOX5APFEN1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9953196 | 0.73 | PIK3CG (0.46) | SMN1; SMN2MEN1KMT2AHTTPOLB | |
| SCHEMBL19303684 | 0.73 | PIK3C2G (0.48) | ALOX5APFEN1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |