Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954020 | 0.85 | PIK3C3 (0.49) | PIK3C3KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL14305926 | 0.83 | PIK3C3 (0.55) | PIK3C3KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL9954686 | 0.83 | PIK3C3 (0.53) | PIK3C3KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL9954276 | 0.81 | ALPL (0.51) | PIK3C3CA1CA2ALOX5APFEN1 | |
| SCHEMBL9953075 | 0.81 | PIK3C3 (0.52) | PIK3C3KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL9954497 | 0.81 | PDE4A (0.54) | CA1CA2ALOX5APFEN1KMT2A | |
| SCHEMBL21760960 | 0.80 | PIK3C2G (0.48) | PIK3C3ALOX5APFEN1KDM4EHSD17B10 | |
| SCHEMBL19303684 | 0.80 | PIK3C2G (0.48) | PIK3C3ALOX5APFEN1KDM4EHSD17B10 | |
| SCHEMBL9953196 | 0.80 | PIK3CG (0.46) | PIK3C3KDM4EHSD17B10KMT2AMEN1 | |
| Pyridine SCHEMBL9955114 | 0.77 | PIK3C3 (0.48) | PIK3C3KDM4EHSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |