Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953536 | 0.81 | DGAT1 (0.32) | — | |
| SCHEMBL9953694 | 0.77 | ALPL (0.34) | ALPLPDGFRBKDRAAK1 | |
| SCHEMBL9954209 | 0.76 | ALPL (0.34) | ALPLPDGFRBKDRAAK1 | |
| SCHEMBL9952972 | 0.76 | ALPL (0.33) | ALPLPDGFRBKDRAAK1 | |
| SCHEMBL9954735 | 0.74 | ALPL (0.33) | ALPLAAK1 | |
| SCHEMBL25316750 | 0.71 | NPC1 (0.35) | — | |
| SCHEMBL30506908 | 0.71 | NPC1 (0.35) | — | |
| SCHEMBL23090811 | 0.71 | DGAT1 (0.32) | AAK1 | |
| SCHEMBL190276 | 0.70 | DGAT1 (0.31) | ALPLAAK1 | |
| SCHEMBL21463604 | 0.69 | GSK3A (0.37) | PDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |