Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954978 | 0.81 | ALPL (0.34) | — | |
| SCHEMBL9954569 | 0.76 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL9955652 | 0.73 | PI4KA (0.54) | — | |
| SCHEMBL9954498 | 0.73 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL9952816 | 0.73 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL9959889 | 0.72 | DGAT1 (0.35) | DGAT1NPC1 | |
| SCHEMBL32686762 | 0.70 | PDE4B (0.38) | DGAT1NPC1KMT2A | |
| SCHEMBL20155429 | 0.68 | DGAT1 (0.34) | DGAT1NPC1 | |
| SCHEMBL30902985 | 0.67 | NPC1 (0.32) | DGAT1NPC1 | |
| SCHEMBL25320858 | 0.67 | HSD17B10 (0.57) | DGAT1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |