⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664171 | 0.70 | — | — | |
| SCHEMBL994996 | 0.68 | — | — | |
| SCHEMBL690325 | 0.66 | — | — | |
| SCHEMBL70153 | 0.65 | CYP2A6 (0.36) | — | |
| SCHEMBL5309 | 0.63 | — | — | |
| SCHEMBL21177747 | 0.61 | CYP2A6 (0.35) | — | |
| SCHEMBL70280 | 0.59 | CYP2A6 (0.31) | — | |
| SCHEMBL184780 | 0.59 | ALDH1A1 (0.32) | — | |
| SCHEMBL10796479 | 0.57 | ALDH1A1 (0.37) | — | |
| SCHEMBL56536 | 0.57 | MAPT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644217-B1 | A process for producing polymers of alpha,omega-unsaturated conjugated compounds, and high molecular weight conjugated polymers thus obtainable | COVION ORGANIC SEMICONDUCTORS (DE) | 2004-06-09 | — | — | EP | claimed |
| US-5374416-A | Nitrogenous macrocyclic ligands, polymetallic complexes and diagnostic and therapeutic composition | GUERBET S.A. (FR) | 1994-12-20 | — | — | US | claimed |
| US-20240197888-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2024-06-20 | — | — | US | disclosed |
| WO-2024120466-A1 | MONOSACCARIDES, PHARMACEUTICAL COMPOSITIONS, AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | SURIO THERAPEUTICS CO., LTD (CN) | 2024-06-13 | — | — | WO | disclosed |
| WO-2024120442-A1 | PAK4 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | CONVERGEN (SUZHOU) PHARMACEUTICAL CO., LTD. (CN) | 2024-06-13 | — | — | WO | disclosed |
| WO-2024120467-A1 | PHOSPHORAMIDATE MONOSACCHARIDES, PHARMACEUTICAL COMPOSITIONS, AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | SURIO THERAPEUTICS CO. LTD (CN) | 2024-06-13 | — | — | WO | disclosed |
| US-20240190883-A1 | KRAS PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2024-06-13 | — | — | US | disclosed |
| US-20240190885-A1 | KRAS PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX INC (US) | 2024-06-13 | — | — | US | disclosed |
| US-20240174643-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2024-05-30 | — | — | US | disclosed |
| CN-118076602-A | Heteroaryl-acetylenes, pharmaceutical compositions thereof and their therapeutic uses | 嘉兴优博生物技术有限公司 | 2024-05-24 | — | — | CN | disclosed |
| WO-2024104384-A1 | INDENE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | NUCMITO PHARMACEUTICALS CO. LTD. (CN) | 2024-05-23 | — | — | WO | disclosed |
| EP-1456210-A1 | PYRAZOLYL-SUBSTITUTED TRIAZOLOQUINOXALINES | JSW-Research Forschungslabor Gmbh (AT) | 2004-09-15 | — | — | EP | disclosed |
| US-20040170866-A1 | Cyclic tertiary amine compound and organic electroluminescent device containing the compound | GUOFANG WANG (JP) | 2004-09-02 | — | — | US | disclosed |
| US-6761981-B2 | HIGH EFFICIENCY AND LONG SERVICE LIFE; MARCROCYCLIC RINGS COMPRISING TERTIARY AMINES CONTAINED IN A HOLE TRANSPORT LAYER AND/OR LUMINESCENT LAYER OF AN ELECTROLUMINESCENT DEVICE SUCH AS FLAT SCREEN DISPLAY | CHISSO CORPORATION (JP) | 2004-07-13 | — | — | US | disclosed |
| WO-2003053973-A1 | PYRAZOLYL-SUBSTITUTED TRIAZOLOQUINOXALINES | JSW-RESEARCH FORSCHUNGSLABOR GMBH (AT) | 2003-07-03 | — | — | WO | disclosed |
| US-20020058155-A1 | Cyclic tertiary amine compound and organic electroluminescent device containing the compound | CHISSO CORPORATION (JP) | 2002-05-16 | — | — | US | disclosed |
| US-6051722-A | PRECURSOR FOR POLYIMIDE COPOLYMER; USABLE IN OPTICAL LONG-DISTANCE COMMUNICATION, SIGNAL PROCESSING, PHOTOELECTRIC HYBRID CIRCUITS AND OPTICAL COMPUTERS | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2000-04-18 | — | — | US | disclosed |
| US-5917003-A | Process for producing polymers of α,ω-unsaturated conjugated compounds, and high molecular weight conjugated polymers thus obtainable | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-06-29 | — | — | US | disclosed |
| US-5834575-A | POLYIMIDE OR POLYACRYLATE WITH PENDANT GROUP CONTAINING THIOPHENE RING, BENZENE RING AND VICINAL NITRILE GROUPS, SWITCHES FOR OPTICAL SIGNALS, COMMUNICATION TECHNOLOGY | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5374416-A | Nitrogenous macrocyclic ligands, polymetallic complexes and diagnostic and therapeutic composition | GUERBET S.A. (FR) | 1994-12-20 | — | — | US | disclosed |