Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957 | 0.70 | CYP2A6 (0.32) | MAPT | |
| SCHEMBL8879 | 0.70 | GPR3 (0.35) | MAPT | |
| SCHEMBL70153 | 0.65 | CYP2A6 (0.36) | MAPT | |
| SCHEMBL5486514 | 0.59 | ALDH1A1 (0.35) | MAPT | |
| SCHEMBL184780 | 0.59 | ALDH1A1 (0.32) | — | |
| SCHEMBL1976862 | 0.57 | — | — | |
| SCHEMBL10796479 | 0.57 | ALDH1A1 (0.37) | MAPT | |
| SCHEMBL995510 | 0.57 | — | — | |
| SCHEMBL994884 | 0.57 | — | — | |
| SCHEMBL1587229 | 0.57 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3651762-B1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | UNIV VANDERBILT (US) | 2024-07-03 | — | — | EP | claimed |
| US-20220048913-A1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY | 2022-02-17 | — | — | US | claimed |
| CN-110891569-A | Antagonists of muscarinic acetylcholine receptor M4 | 范德堡大学 | 2020-03-17 | — | — | CN | claimed |
| US-6686134-B2 | REDUCING STAIN FROM SENSITIZING DYES DURING SILVER HALIDE COLOR DEVELOPMENT USING NITROGEN AROMATIC HETEROCYCLIC DERIVATIVE WHICH IS LOW TEMPERATURE STORAGE STABLE | FUJI PHOTO FILM CO., LTD. (JP) | 2004-02-03 | — | — | US | claimed |
| US-20030224300-A1 | Photographic processing composition containing heterocycle combination and method of forming image | FUJI PHOTO FILM CO., LTD. | 2003-12-04 | — | — | US | claimed |
| US-20030054298-A1 | Photographic processing composition containing heterocycle combination and method of forming image | FUJI PHOTO FILM CO., LTD. | 2003-03-20 | — | — | US | claimed |
| US-6313247-B1 | Cinchonan based chiral selectors for separation of stereoisomers | LINDNER WOLFGANG (AT) | 2001-11-06 | — | — | US | claimed |
| EP-0912563-A1 | CINCHONAN BASED CHIRAL SELECTORS FOR SEPARATION OF STEREOISOMERS | Lindner, Wolfgang, Prof. Dr. (AT) | 1999-05-06 | — | — | EP | claimed |
| WO-1997046557-A1 | CINCHONAN BASED CHIRAL SELECTORS FOR SEPARATION OF STEREOISOMERS | LINDNER WOLFGANG (AT) | 1997-12-11 | — | — | WO | claimed |
| EP-0776905-A2 | Process for the preparation of (24R)-24,25-dihydroxysteroid compounds | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-06-04 | — | — | EP | claimed |
| US-5374416-A | Nitrogenous macrocyclic ligands, polymetallic complexes and diagnostic and therapeutic composition | GUERBET S.A. (FR) | 1994-12-20 | — | — | US | claimed |
| US-5081245-A | Selective antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | claimed |
| EP-3651762-B1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | UNIV VANDERBILT (US) | 2024-07-03 | — | — | EP | disclosed |
| US-20240197888-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2024-06-20 | — | — | US | disclosed |
| WO-2024120442-A1 | PAK4 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | CONVERGEN (SUZHOU) PHARMACEUTICAL CO., LTD. (CN) | 2024-06-13 | — | — | WO | disclosed |
| WO-2024120466-A1 | MONOSACCARIDES, PHARMACEUTICAL COMPOSITIONS, AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | SURIO THERAPEUTICS CO., LTD (CN) | 2024-06-13 | — | — | WO | disclosed |
| US-5081245-A | Selective antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0356765-A2 | Carboxylic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-03-07 | — | — | EP | disclosed |
| US-4226951-A | AROMATIC HETEROCYCLE COUPLER | GENERAL ELECTRIC COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| US-4156771-A | Process of forming heterocyclic-coupled block polymers of polyphenylene oxide | GENERAL ELECTRIC COMPANY (US) | 1979-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048913-A1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | CHRM2, CHRM4, CHRM3 | MAPT 2224/4885 |
| US-20240197888-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | SOS1, SOS2, SOST | MAPT 989/4885 |
| US-20030054298-A1 | Photographic processing composition containing heterocycle combination and method of forming image | PRXL2A, ENY2, RB1 | MAPT 3856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.