Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 3/20 | 0.36 |
| ▸ | CASP7 | P55210 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954047 | 0.91 | HSD17B10 (0.41) | HSD17B10ALDH1A1CYP1A2CYP2D6CASP1 | |
| SCHEMBL9953325 | 0.87 | HSD17B10 (0.49) | HSD17B10ALDH1A1CYP1A2CYP2D6CASP1 | |
| SCHEMBL10289053 | 0.82 | KDM4E (0.50) | HSD17B10ALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL31241102 | 0.82 | CACNA2D1 (0.42) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL31241091 | 0.75 | CACNA2D1 (0.47) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL9954454 | 0.73 | MEN1 (0.41) | HSD17B10ALDH1A1CYP1A2CYP2D6CASP1 | |
| SCHEMBL9954050 | 0.72 | HSD17B10 (0.41) | HSD17B10ALDH1A1CYP1A2CYP2D6CASP1 | |
| SCHEMBL10289136 | 0.72 | CACNA2D1 (0.51) | CYP1A2CYP2D6MEN1KMT2ACASP3 | |
| SCHEMBL9955108 | 0.71 | MEN1 (0.40) | ALDH1A1MEN1KMT2ACYP3A4GAA | |
| SCHEMBL9954166 | 0.71 | ALDH1A1 (0.42) | HSD17B10ALDH1A1CASP1CASP7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |