Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | CASP7 | P55210 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9960599 | 0.80 | MAPK1 (0.49) | ALDH1A1GAAGLAKDM4ECASP1 | |
| SCHEMBL31241102 | 0.76 | CACNA2D1 (0.42) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL9954169 | 0.76 | FLT3 (0.42) | ALDH1A1GAAGLAKDM4ECASP1 | |
| SCHEMBL9954047 | 0.76 | HSD17B10 (0.41) | ALDH1A1GAAKDM4ECASP1CASP7 | |
| SCHEMBL9953779 | 0.74 | ALOX15 (0.55) | ALDH1A1GAAKDM4EMAPK1ALOX15 | |
| SCHEMBL9954190 | 0.73 | CACNA2D1 (0.36) | ALDH1A1KDM4EHPGDLMNAHTT | |
| SCHEMBL9955265 | 0.71 | HSD17B10 (0.41) | ALDH1A1GAAGLAKDM4ECASP1 | |
| SCHEMBL9952861 | 0.70 | TDO2 (0.46) | ALDH1A1KDM4ECASP7HSD17B10MAPK1 | |
| SCHEMBL9954454 | 0.70 | MEN1 (0.41) | ALDH1A1GAAKDM4ECASP1HSD17B10 | |
| SCHEMBL4743465 | 0.70 | ALDH1A1 (0.56) | ALDH1A1GAAKDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |